Reza Basiri

Research

MSc thesis, January 2018 Open access

Method for Optimizing Quantitative Temporal Lobe Epilepsy MR Imaging

Reza Basiri

University of Calgary. DOI 10.11575/PRISM/5418

In brief

Standard MRI can miss the subtle hippocampal changes behind temporal lobe epilepsy. This thesis develops a leaner stimulated echo correction for T2 relaxometry and tests it on simulated and patient data, with the goal of making those lesions easier to find.

Key findings

  • Up to 27% lower variance than the original stimulated echo correction
  • More reliable classification of abnormal hippocampal regions
  • The groundwork for the 2019 MAGMA paper

Read at the publisher

Related work

  1. Transverse relaxometry with transmit field-constrained stimulated echo compensation

    Reza Basiri, Paolo Federico, Robert Marc Lebel

    Journal article. Magnetic Resonance Materials in Physics, Biology and Medicine (MAGMA), 32(6), 669-677, 2019

    Quantitative T2 maps can reveal subtle tissue changes, but real scanners never produce the clean exponential decay the standard fit assumes. Stimulated echo correction fixes the bias at the cost of noisier estimates. This paper's two-step method uses the fact that the transmit field varies smoothly across the head, fixing it in a second pass so each voxel fits fewer free parameters.

    SummaryPublisher

  2. Focal epilepsy without interictal spikes on scalp EEG: A common finding of uncertain significance

    Reza Basiri, Aidin Shariatzadeh, Samuel Wiebe, Yahya Aghakhani

    Journal article. Epilepsy Research, 150, 1-6, 2019

    Doctors use interictal spikes on EEG to locate and classify epilepsy, but not every patient shows them. Reviewing seven years of video-EEG monitoring at the Calgary Epilepsy Program, this study measured how often adults with focal epilepsy never spike on scalp EEG and whether they differ clinically from those who do.

    SummaryPublisher

  3. Method for Optimizing Quantitative Temporal Lobe Epilepsy MR Imaging

    Reza Basiri, Paolo Federico, Robert Marc Lebel

    Conference abstract. Calgary Epilepsy Research Retreat, 2016

    An early report of the optimized T2 relaxometry method and its use for temporal lobe epilepsy imaging, presented to Calgary's epilepsy research community.

    Summary